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What does DogCheck 4
Mutation: BEST1 gene
the presence of multiple variants on a single copy of the gene cannot be excluded
Trägern und gesunden Hunden
abdomen and legs
Progressive Retinaatrophie, Autosomal dominant (PRA-AD) - Mastiff Hundebesitzer What does DogCheck 4Progressive retinal atrophy (PRA) in dogs is a group of genetically heterogeneous inherited retinal disorders characterized by progressive degeneration and death of photoreceptor cells. PRA in English Mastiffs and Bullmastiffs (AD PRA) is an autosomal dominant disorder of rhodopsin, the visual pigment of rod photoreceptors. Rod vision can be normal early in life and degeneration slowly spreads. Degeneration of the retina can be identified in puppies
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