Au HCT, Zheng YJ, Le GH, Wong S, Phan L, Teopiz KM, Kwan ATH, Rhee TG, Rosenblat JD, Ho R, McIntyre RS (2025) A systematic review in effects of glucagon-like peptide-1 (GLP-1) mono-agonists on functional connectivity: Target engagement and rationale for the development in mental disorders
Employing a high-dimensional propensity score algorithm to adjust for confounders, this study found no significant increase in depression or self-harm rates among GLP-1RAs users
147157 (Springer Berlin Heidelberg, 2011)
Open package, eat, done
When chyme delivers amino acids, fatty acids, and fermentable carbohydrates farther down the tract, L-cells release incretin peptides into the bloodstream and toward neural pathways that influence appetite