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Satoh MS et al
B12 injections deliver the vitamin directly into the bloodstream, ensuring maximum absorption and immediate effects, whereas oral supplements must pass through the digestive system, which can result in lower absorption rates and slower onset of action
, and this route of absorption is unaffected in patients with pernicious anemia
Vegans and Vegetarians Since B12 is found almost exclusively in animal-based foods, individuals following plant-based diets are at a higher risk of deficiency
In practice, some people with B12 deficiency may be able to switch to very high dose (e.g
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