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While originally developed for diabetes management, their profound effects on weight have made them a valuable tool for those struggling with weight, including women navigating menopausal changes

Compared to L-arginine, an advantage to supplementation with L-citrulline is that intestinal catabolism of L-citrulline is limited since it is not metabolized by arginases, and the activity of arginosuccinate synthase is low in enterocytes [2]

The combination of protein and fiber will help keep you full, support gastrointestinal (GI) function, and promote muscle maintenance

For context, Roux-en-Y gastric bypass surgery weakens this circuit by approximately four-fold, which partly explains why surgical outcomes often exceed pharmaceutical ones in total weight lost

GLP-1 medications reduce appetite dramatically