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Hence, in general, the stability of formyl- and/or oxidized forms is much higher than that of methyl- and/or reduced ones, and the acidic environment accelerates the thermal decomposition 66,106,234,346,363,364,365,366,367,368,369,370,371,372,373,374

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Because of their different protective actions, these two drug classes may have additive effects that help preserve beta cells