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The drug gained FDA approval in 2003 after showing efficacy in clinical trials
Plasma SPARC levels positively correlate with lumbar spine BMD, and 12 months of recombinant human parathyroid hormone (134) treatment in osteoporotic patients increases the circulating SPARC level, which is associated with changes in lumbar BMD at L2-L4 [24]
Custer said that most of those effects occur while people are starting the medication or increasing their dose
Therefore, DA signals mediated by D1Rs might be involved in aberrant Glu-Gln cycles and the consequent dysregulation of the neuronal E/I balance in autism
PubMed laboratory research record [PMID: 41494820] PubMed record related to this compound for laboratory literature review
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