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The drastic inhibition of GLP-1 secretion via shutdown of the main pathway is the primary cause of pasireotide-induced hyperglycemia

Histidine and lysine produced significantly more pigment than arginine under identical conditions, and a Box-protective lysine (Boc-Lys), which preserves the -NH 2 group, yielded deeper pigmentation than unprotected lysine, implicating the -amino group of lysine as a key reactive site

Jacobson TA, Maki KC, Orringer CE, Jones PH, Kris-Etherton P, Sikand G, et al

The required daily dosage shall not be the one contained in one or two fruits only

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