bloated stomach glp 1 GLP-1 Side Effects: When to Call a Doctor Managing GI Discomfort on GLP-1s:

Secreted INSL-5 acts on the Relaxin/Insulin-like family peptide receptor 4 (RXFP4) (166), which is expressed along the GI tract, the nodose ganglion and the enteric nervous system (164), and inhibits adenylyl cyclase activity (167)

For changes of more than one day, consult your provider

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Asmar A, Simonsen L, Asmar M, Madsbad S, Holst JJ, Frandsen E, et al