Leptin is an important hormone, made only by fat tissue, that is an important regulator of metabolism, so leptin therapy made intuitive sense in patients with CGL
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This multicountry trial was conducted in accordance with the International Conference on Harmonization Good Clinical Practice guidelines and the Declaration of Helsinki and was approved by local institutional review boards
8,129,343, which covers the semaglutide compound itself, pharmaceutical compositions containing it, and methods of treatment using those compositions
Rome: I.N.C., 1998: 4457 Quigley HA, McKinnon SJ, Zack DJ, et al