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GLP-1R knockout mice (GLP-1R KO, Shanghai Model Organisms, based on C57BL/6N) were generated using CRISPR/Cas9 technology, which causes Glp1r gene protein reading frame shift and loss of function by using non-homologous recombination repair to introduce mutations

They also assessed conjugated bile acids and free bile acids levels in BCS and the various NBC groups

A patient came to my office recently and told me she had stopped her statin

Managing hemophilia requires a careful approach, especially when considering new medications

Mechanism-focused studies may include receptor-pathway assays, biomarker panels, gene-expression analysis, protein-expression studies, cell-viability controls, migration assays, metabolic marker analysis, or stability testing