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The differential effects observed across brain regions suggest that liposomal deliverymay reflect differences in regional susceptibility or indirect systemic effects rather than confirmed differential brain distribution
Its core mechanism lies in mitochondrial regulation, which specifically involves reducing mitochondrial damage, regulating apoptosis and oxidative stress-related pathways, and transmitting protective signals via humoral factors (176, 177)
I stopped taking PPIs years ago, however I was briefly on a GLP-1 for about two months a couple of years agoand I can completely can understand where it would interfere with the efficacy of a PPI
However, this might be consequential to the fatty acid sidechain 38 and not related to NMDA receptor modulation (Extended Data Fig
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