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In addition, ALOXs can directly or indirectly promote lipid oxidation in cell membranes to increase the sensitivity of cells to ferroptosis, especially under the catalysis of ferrous iron [34, 35]

Genetic polymorphisms of alcohol and aldehyde dehydrogenases and glutathione S -transferase M1 and drinking, smoking, and diet in Japanese men with esophageal squamous cell carcinoma, Carcinogenesis , Volume 23, Issue 11, November 2002, Pages 18511859, For answers or to make an appointment, call us toll-free at 800-923-7878 to speak with a Patient Care Team

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