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Outcomes referenced from STEP 1 and SUSTAIN clinical trial data

Outcomes and covariates The primary outcomes were the incidence of herpes simplex infection (ICD-9-CM codes 054, ICD-10-CM code B00) and herpes zoster infection (ICD-9-CM codes 053, ICD-10-CM code B02)

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Gastrointestinal side effects such as diarrhoea are most common during the dose-escalation phase of retatrutide treatment and often improve or resolve once a stable maintenance dose is reached