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This finding has implications for how long to stay on semaglutide for weight loss and understanding semaglutide withdrawal symptoms
PLOS ONE 9 , e98520 (2014)
The primary endpoint of the study (the pre-determined measure of success for the study) was the changes in the MDS-UPDRS (part III) motor score and the change in non-motor symptoms (as assessed by the NMSS and MDRS-2) after 52 weeks of treatment ( Click here to read more about this study)
To validate this structural effect, it will be necessary to use an animal OA rodent model, such as the surgical destabilization of the medial meniscus (DMM), which is a more acceptable and suitable model to study the effects of liraglutide on cartilage degradation 56
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