A 36-year-old man with history of anxiety, obsessive compulsive disorder (OCD), and tic disorder (on treatment with sodium valproate 300 mg for the past 6 months, risperidone 2 mg/day for 2 years, and haloperidol for the last 3 days) was referred to us after becoming drowsy and unresponsive over the previous 2 days following disproportionate drowsiness after administration of haloperidol and promethazine for acute aggressive behavior, retching, and vomiting
It offers no therapeutic benefit
Leading companies continue to focus on developing new and improved molecules with shorter dosing frequency and improved safety and tolerability, reducing the performance gap with injectable medications
Studies in Gastroenterology showed that oral KPV reduced inflammation in colitis models
Tafuri A, Bondi D, Princiotta A, Pietrangelo T, Yadav P, Altieri VM, et al