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Psoriasis has increasingly been linked to metabolic disorders such as diabetes, obesity, and dyslipidemia [199, 200]
This dual action makes it an effective option for individuals struggling with obesity or those who need to lose weight to manage their diabetes better
Palmitoylation A reversible lipid post-translational modification in which palmitate is added to cysteine residues of proteins
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used for chronic weight management, along with a reduced calorie diet and increased physical activity, for people with an initial body mass index (BMI) of: 30 kg/m2 or greater (obesity) or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition (e.g., hypertension, type 2 diabetes mellitus, or dyslipidemia)
[4], who attributed GLP-1RAs related cholelithiasis to the reduced cholycystokinine mediated gallbladder emptying and prolonged gallbladder refilling that may induce complicated cholelithiasis
