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For MCAS and year-round histamine issues, longer-term protocols are more common

And if youre losing fluid through vomiting or diarrhea side effects, dehydration can happen and, in some cases, can even become severe enough to cause kidney problems

In our practice, we focus less on the label and more on what your imaging suggests (diffuse vs focal/adenomyoma, junctional zone changes, uterine size) and what your goals are (pain control, bleeding control, fertility preservation, or definitive treatment)

But if they dont have any of those conditions, I think we should prioritize these newer injectable medications, which are such profound weight loss and metabolic benefits. Majety said the network meta-analysis was comprehensive, but more data are needed to assess the potential loss of lean body mass with obesity medications