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2 More severe obesity, defined as a BMI above 40, can cut eight to ten years from expected lifespan
Metabolic syndrome, a closely related condition characterized by central obesity, insulin resistance, dyslipidemia and hypertension, further amplifies cardiometabolic risk[5]
Thankfully, most people find the sensation improves as their body adjusts
Balonov I et al
In Phase 3 clinical trials, participants on retatrutide lost up to 28.7% of their body weight in 68 weeks
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