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Male C57BL/6J mice were anaesthetized with i.p

Because many previous reports demonstrated that hypertension alone induces a shift from fatty acid oxidation toward increased glucose utilization in cardiac muscle, hypertension complicated with HFpEF might have additive effects on energy metabolic failure in heart

Vitamins are organic compounds that are essential in small amounts for normal metabolism

Think of it as an internal corset

The armed forces estimate that during a chemical attack, many personnel may be exposed to 5 times the lethal dose (LD) of soman, so a protective ratio (that raises the LD) by at least 5 times is needed