Any appetite-related changes are secondary: as sleep improves, energy returns, and body composition shifts, patients naturally feel more motivated to support those changes with better nutrition
It's not this huge burst of inflammation that you get from something like exercise where your body is responding to that with an anti inflammatory response
Extensive clinical trials conducted during the drug's development, including the SUSTAIN programme, involved thousands of patients with type 2 diabetes followed over several years
Historically, this increased insulin response mediated by GLP-1 and GIP had been attributed to factors termed incretins (derived from incretion, a term used at that time to refer to a secretion that remains inside the body), hence the name incretin effect is still used today to describe the rise in insulin mediated by the action of these hormones
You are not swallowing a pill on an empty stomach every morning