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Phase 3 trial discontinuation rates are useful, but real-world data tend to show different patterns once a drug is widely prescribed

Our Scientific Advisors review existing data and use the Developability Classification System to assess whether a molecules oral absorption is likely to be limited by solubility, dissolution rate, permeability or dose

A doctor may adjust the medication dose, slow the titration schedule, review food timing, change constipation support, check labs, assess hydration, evaluate other medications, or pause treatment when needed

Ultimately, patients may be looking for a softer landing than stopping altogether

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