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Considering their low MW and non-covalent nature of inhibition of TGR, these compounds were deemed appropriate for fragment-based design

This has led to a dramatic increase in body contouring procedures, with liposuction searches increasing 144% year-over-year among GLP-1 users seeking to refine their results

Method validation results showed good linearity (R20.9963) ranging from 5 to 1000 ng/mL

Rare but important risks include pancreatitis, gallbladder problems, dehydration from severe vomiting/diarrhoea, and potential worsening of diabetic eye disease in people with diabetes

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