These newly identified metabolites may also be translated to other more targeted methods that are faster and less costly than NMR, such as biosensors or immunoassays (32, 33)
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These continuously generated electrophilic hydroperoxy-phospholipids are neutralized by a specific GSH-dependent peroxidase, glutathione peroxidase 4 (GPX4), which prevents them from damaging membranes and driving ferroptotic cell death (7, 8)
Like other NADs, researchers have focused on nanocarriers based on liposomes, chitosan, and other materials to achieve efficient delivery, laying a solid foundation for the clinical application of the CRISPR/Cas9 system