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Since most of the actions of tamoxifen are mediated via ER, ER expression has been considered a prognostic marker for tamoxifen effectiveness and therefore loss of ER expression is associated with de novo drug resistance

Specificity Sample Types validated: Whole Blood, Serum, Plasma,Erythrocytes, Urine, Cell Lysates and Tissue Samples Sensitivity 0.634 M Characteristics The Glutathione (GSH) kit utilizes a colorimetric substrate that reacts with the free thiol group on GSH to yield a highly colored product

j , Top, schematic of proteoliposome reconstitution validation

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