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This peptide binds to a specific receptor on the surface of beta cells in the pancreas, causing them to release insulin, and for a long time researchers assumed that GLP-1 analogues only affected insulin release, hence why they were prescribed for type 2 diabetes
[1] [2] This dual agonist mechanism distinguishes tirzepatide from other diabetes medications and contributes to its glycemic control capabilities
September 2023: Ileus and intestinal blockages were added
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Similarly, conducting research like this to evaluate whether tirzepatide can help slow kidney disease could potentially lead to a label expansion from the FDA for chronic kidney disease as well
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