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Moreover, this silencing resulted in mitochondrial depolarization, evident from the conversion of JC-1 red aggregates to green monomers (Fig
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Senescent Chondrocyte Removal & Chondrogenic Potential Restoration (PMC, 2021) FOXO4-DRI Removes Replication-Stress Senescent Chondrocytes in ACI Research Model A study published in PMC investigated FOXO4-DRI in the context of autologous chondrocyte implantation (ACI) a procedure in which in vitro chondrocyte expansion generates a senescent cell burden that adversely affects cartilage formation quality and quantity
doi:10.1210/jc.2002-021603 Rabijewski M, Zgliczynski W
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