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Also, genetic modifiers of poly GR toxicity in Drosophila identified APE1 and other DNA repair proteins (Ku80 and ERCC1) as suppressors of GR toxicity (Lopez-Gonzalez et al., 2019)
Schwartz K, Chang HT, Nikolai M, Pernicone J, Rhee S, Olson K et al
For instance, in the DUAL VII study, 35% of those taking Xultophy achieved an A1C below 7% without hypoglycemia or weight gain, compared to only 5% of participants using basal-bolus insulin
However, you should always consult your healthcare provider before adding any medications or supplements to ensure safety and appropriateness for your specific situation
PubMed PMID: 38346988
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