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As with Keshan disease, KBD is prevalent in selenium-deficient provinces and thus generally affects people with very low selenium intakes (58, 59)

106 Despite stimulated glucose uptake, insulin rapidly reduces hepatic glucose output and hepatic glucose production (HGP) by activating glycogen synthesis, and suppressing glycogenolysis and gluconeogenesis in liver

The right dose for a 30-year-old athlete with an acute Achilles strain is different from the right dose for a 55-year-old patient in post-surgical recovery