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The array sensitivity analysis showed that an unmeasured confounder would again need to have at least 15% imbalance and a confounder-outcome association of 3.5 or 30% imbalance and a confounder-outcome association of 2.0 to bias results by 25% or more (supplementary figure S3B)

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The administration of liraglutide significantly attenuated PCOS-associated ovarian MGCs apoptosis in a concentration-dependent manner, and these effects were associated to modifications of the phosphorylation sites of forkhead box protein O1 (FoxO1), a negative regulator of cell survival