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In this review, we summarize the current existing literatures on NADPH metabolism, including its biological functions, regulatory mechanisms, and the corresponding therapeutic interventions directly or indirectly targeting NADPH metabolism in cancer

It serves as a substrate for glutathione S-transferase enzymes, which bind reactive compounds and metabolic byproducts to facilitate their elimination

it has been shown to reduce the risk of cardiovascular events and macrovascular disease (Kooy et al, 2009

Increased metabolism

After 8 h of transfection, the medium was changed by fresh ECM containing 5% FBS and cells were harvested or used for further study in vitro after 48 h