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Unlike traditional insulin secretagogues, Prusogliptin does not directly stimulate insulin release but rather enhances endogenous GLP-1 activity, resulting in a lower risk of hypoglycemia and less likelihood of weight gain

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De AK, Muthiyan R, Mondal S, Mahanta N, Bhattacharya D, Ponraj P, Muniswamy K, Kundu A, Kundu MS, Sunder J, et al

Maximal mitochondrial respiration and reserve capacity were strikingly enhanced by Exendin-4 preconditioning (Fig

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