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Parkinsonism Relat Disord 22(Suppl 1):S41-46 Schaffner A et al (2019) Vitamin B12 modulates Parkinsons disease LRRK2 kinase activity through allosteric regulation and confers neuroprotection

TAB2, TAK1-binding 2

Rats tolerated doses far exceeding those used therapeutically without mortality or obvious adverse effects

Difficulty walking or balance problems : Nerve damage caused by B12 deficiency can lead to difficulty walking, balance problems, and even muscle weakness

The correction of megaloblastic anemia with vitamin B12 can result in fatal hypokalemia and gout in susceptible individuals, and it can obscure folate deficiency in megaloblastic anemia