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placebo for 26 weeks and demonstrated a greater efficacy in terms of reduction of body weight and waist circumference (WC) in the liraglutide group [54,55,56]

The most common side effects reported in trials include: Digestive issues Nausea (the most frequently reported side effect) Vomiting Diarrhoea Constipation Stomach pain or discomfort Loss of appetite Other reported effects Fatigue or tiredness Injection site reactions (redness, swelling, or irritation) Most side effects tend to be worse when starting the medication or increasing the dose, and often improve as your body adjusts

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Safety and Side Effects While generally well-tolerated, there are some common side effects of GLP-1 agonists

Simultaneously, resting metabolic rate drops by 28% per decade after age 30, accelerating during perimenopause and early postmenopause