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Bipolar disorder similarly exhibits disruption of the Firmicutes / Bacteroidetes ratio and reduced -diversity, featuring increased Streptococcaceae and Bacteroidaceae abundance contrasting with depletion of anti-inflammatory commensals such as Faecalibacterium ( 249).Among neurodegenerative disorders, Parkinsons disease shows increased abundance of Lactobacillus and Bifidobacterium with concurrent reduction in Faecalibacterium , Coprococcus , and Blautia ( 250, 251), where decreased Blautia abundance correlates with clinical severity and reduced fecal butyrate levels (252)

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No other currently known proteins have the same overall topology as GST enzymes

For the body's fat metabolism , carnitine plays a particularly important role, as long-chain fatty acids can only be transported into the mitochondria (the cell's powerhouses) when bound to L-carnitine

In addition to providing structure, collagen also plays an important role in tissue development and regulation (6, 7)