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M2022-04)

To achieve sufficient glutamine, cancer cells must uptake glutamine from the extracellular environment through specific transporters on the cell membrane, such as the alanine-serine-cysteine transporter 2 (ASCT2), also known as SLCA15 (Scalise et al., 2017)

In this Review, we discuss similar preclinical studies that present novel concepts in the neural control of food intake and body weight, with reference to endogenous GLP-1, GLP-1R agonists, and bariatric surgeries like Roux-en-Y gastric bypass (RYGB) and vertical sleeve gastrectomy (VSG), which remain the most effective treatments for severe obesity [9]

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