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The difference between the population recruited for an RCT as compared to our study population impacts our findings in two clear ways

If you experience symptoms of depression, such as persistent sadness or loss of interest, or symptoms of anxiety, like excessive worry or restlessness, its important to discuss these with your healthcare provider

Rare side effects: itching, exanthema, chills, fever, hot flushes, nausea, dizziness, and very rarely anaphylaxis

The mechanism is the same

Regarding L-theanine specifically, we read more than 300 scholarly articles pertaining to L-theanine supplementation and the science behind sleep, cognition, mood, and other aspects of life that L-theanine may be able to improve