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Many surgeons recommend reaching a stable weight before considering excess skin removal surgery

Disclosures Yoshifumi Saisho received honoraria from Takeda Pharmaceutical Co

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Daiichi Sankyo supported its NDA, accepted last Fall, with data from a Phase III trial that showed the quizartinib regimencombined with standard induction and consolidation chemotherapy and continued as a single agent)reduced the risk of death by 22.4% compared to patients on chemotherapy alone

The bulk of data sits in rodent models, with the brain-gut axis as the theoretical framework that connects the peripheral and central effects