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An intracellularly expressed single-chain variable fragment targeting mitochondrial CD147 (mito-CD147 scFv) effectively disrupts the mitochondrial CD147/MCT1/LDHB complex, inhibits lactate-induced stemness potential, depletes circulating breast cancer cells, and reduces metastatic burden, suggesting promising clinical applications in reducing lactate-fueled metastasis
Two peptides in particular BPC-157 and TB-500 have gained significant attention from patients, athletes, and clinicians alike
Supporting that pathway improves natural detox capacity and complements our approach to gut health
Flow cytometry was further applied to observe the cellular uptake of nanoparticles
Telomeres, the protective caps at the end of chromosomes, naturally shorten with age, leading to cellular aging and reduced function
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