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86:e03004-19
Clostridium perfringens epsilon toxin binds to erythrocyte MAL receptors and triggers phosphatidylserine exposure
Increased infiltration of local neutrophil extracellular traps (NETs) around intestinal microvasculature, accompanied by increased ferroptosis of endothelial cells, was detected in both intestinal I/R patients and animal models, which may be a major cause of microcirculation dysfunction
Therefore, the authors postulated that the GLP-1-induced vasodilation might reduce total peripheral resistance, leading to a reflex tachycardia [39]
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