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The reduction of the melanin index with glutathione was statistically significant when compared to placebo [Table - 1]

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Its anti-inflammatory effect may be mediated through inhibition of phospholipase A2 activity ( DG, an ammonium salt form of glycyrrhizin, is derived from the glycyrrhizin modified in the two carboxyl groups at the 6and sixposition (Figure 2) (Zhu et al., 2012)