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they can also disrupt ongoing metabolic processes
Acyl-CoA is catabolized in the -oxidation pathway to generate acetyl-CoA, which enters the citric acid cycle
The disease is characterized by severe gastrointestinal dysmotility, sensorimotor peripheral neuropathy, severe muscle weakness, and progressive leukoencephalopathy, with patients usually dying from a combination of nutritional failure and muscular disability
No two patients are the same
Growth hormone & IGF research: official journal of the Growth Hormone Research Society and the International IGF Research Society , 19 (5), 426431
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