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Hydrate more and reduce the dose until symptoms settle
The first few weeks focus on your body readjusting to the medication
FAQs Does semaglutide cause nausea, and how can I manage it
A separate ENDO 2026 study, also reported by ScienceDaily, found that people with obesity who lost weight on GLP-1 drugs became significantly less physically active a counterintuitive finding suggesting that medication-driven weight loss does not automatically produce the behavioral changes needed to maintain it independently
Patients should not adjust doses without medical supervision, and healthcare teams remain the best resource for exploring whether this approach is appropriate
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