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J Gerontol a Biol Sci Med Sci

After five years of follow-up in patients with T2DM, the GLP-1 RAs and SGLT-2 inhibitors groups demonstrated significant reductions in mortality, CHD, HF, AF, stroke, peripheral vascular disease, and CKD, regardless which one of the drugs or its combination were used

Lixisenatide comprises 44 amino acids and is based on the Ex-4 peptide sequence, omitting proline at position 36 and adding six lysine residues at the C-terminal (110)

GLP-1, or glucagon-like peptide-1, is a naturally occurring hormone in the human body that plays a critical role in regulating blood sugar levels, appetite, and insulin secretion

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