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Symptomatic complicated cholelithiasis prevailed in 33.3%
Next, to analyse the functional impact of SPHKAP downregulation on islet function, we employed a lentiviral shRNA approach to knock-down SPHKAP on intact islets, as most functional outputs from primary islets cannot be optimally recapitulated with dispersed islet cells due to the loss of important intra-islet cell-cell interactions
10.1016/j.rvsc.2019.02.004 226 WangJ
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