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G-401, G-402, KMRC-1, OVISE, KP-4, and JMU-RTK-2 cells were obtained from the Japanese Collection of Research Bioresources (JCRB) Cell Bank
Inner BRB breakdown lets lipoproteins leak into retina, raising retinal cholesterol, while the outer BRBretinal pigment epithelium (RPE)transports cholesterol from choroid
However, under more extreme conditions such as: 1) inadequate intake of foodstuffs containing the antioxidants, 2) excessive intake of pro-oxidants, 3) exposure to noxious chemicals or ultraviolet light, 4) injury/wounds, and/or 5) intense exercise, especially eccentric exercise, the body's endogenous antioxidant system is not able to effectively remove excessive ROS production[2]
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