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10.1016/j.bbamcr.2012.06.019 Biochim Biophys Acta
From a clinical perspective, adequate GLP-1 signaling contributes to maintaining normal blood glucose levels and healthy body weight
In research contexts, it is studied as a discrete pentadecapeptide with reproducible physicochemical properties, allowing its use in biochemical, cellular, and preclinical experimental systems
The fusion product is resistant to DPP-4 degradation, due to an alanine to glycine substitution at position 2 (A2G) in each of the peptide sequences 28,29 , and has a plasma half-life of five days on average in humans 30,31,32
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