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A pH-responsive metal-organic framework for the co-delivery of HIF-2 siRNA and curcumin for enhanced therapy of osteoarthritis
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The differentiation of activated nave CD4 + T cells into Th17 cells is severely impaired in glutamine-free medium, but Treg cell formation is normal and even appears to be enhanced in expression (49)
(2) Mitochondrial dysfunction in DAAs and reactive astrocytes Impaired oxidative phosphorylation (OXPHOS) DAAs exhibit reduced mitochondrial respiratory chain activity, leading to decreased ATP production via OXPHOS
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