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These findings are consistent with previous evidence suggesting that although GLP-1 receptor agonists improve lipid parameters, they are often insufficient to achieve guideline-recommended lipid targets without additional lipid-lowering therapy [21, 22]

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Structural characterization of bovine TST (rhodanese) has been extensively performed ( FIGURE 13 To date, no selective small-molecule inhibitor of TST suitable for mechanistic analysis in cells or tissues has been reported