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Therapeutic strategies targeting lipid rafts (e.g., statins, sphingomyelinase inhibitors) stabilize rafts and protect the blood-brain barrier, while SOCE inhibitors and TRP channel antagonists show potential in alleviating microglial inflammation

Inflammation 48 , 40624079 (2025)

One 2015 study demonstrated the way Glutathione protects against oxidative stress

Understanding these mechanisms is essential for developing targeted treatments to alleviate low back pain and prevent further degeneration in patients with OTLFK