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Under the influence of IL-4 and IL-13 and the interactions between adhesion molecules on B cells (class II MHC molecules: CD80/CD86, CD40, and ICAM-1) and T cells (CD3, CD4, CD28, CD40L, and LFA-1 receptors), B cells switch from expressing IgM, IgG2, and IgG3 to IgG4 and IgE (179)

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On the other hand, NAC might increase the chance of pregnancy (Reference Maged, Elsawah and Abdelhafez8,Reference Hassan, Alalfy and Hassan18)

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Experimental evidence suggests that caspase-3 can proteolytically degrade the N-terminal cytoplasmic domain of AE1 [93, 94]